类风湿性关节炎血液测试 - 它们是什么意思?

经过Lene Andersen, MSW 病人倡导者

RF. ESR. Anti-CCP.安娜。CPR。不,这些不是秘密代理商使用的代码来传达他们的任务。它们是用于诊断和诊断的血液测试的名称managing rheumatoid arthritis。When you’re new to this disease, they can seem as mysterious and impenetrable as a secret language. What do they measure? What do the numbers mean? What’s normal, what isn’t? This post is all about demystifying RA blood tests.

类风湿性关节炎血液测试

当医生试图找出你是否有RA,以及如何管理疾病的指标,有许多血液测试。一些最常见的血液测试是:

类风湿因子(RF)

RF is a type of antibody that may be associated with inflammation. This is usually one of the first tests your family doctor will order if they suspect you might have inflammatory arthritis. However, it’s important to know that 20-30 percent of people withRA.are negative for RF (also called seronegative).

它在其他条件下也可能是阳性的,包括Sjogren和结核病,并且少量的健康人也可能测试正面。可以以两种方式报告正常结果,小于40-60 u / ml或小于1:80(1至80)滴度(滴度表达浓度水平)。

抗核抗体(ANA)

ANAis another blood test used when doctors suspect inflammatory arthritis. If positive, it is an indication that more specific investigation is necessary to identify the particular type of inflammatory arthritis.

ana特别发现在狼疮的人中,但也存在于RA,某些感染,胃肠疾病等中。结果在滴度中报告,低水平在1:40至1:60的范围内。

红细胞沉积率(ESR)

也称为sed率,ESR.测量快速红细胞粘在一起并沉淀成沉积物。速率越高,体内存在越多。

男性中正常水平小于15毫米/小时,女性少于20毫米/小时。

C-反应蛋白(CRP)

Along with the ESR, the CRP tests the level of inflammation in the body. It measures the特定蛋白质的浓度在急性炎症期间在肝脏中产生。

普通范围大约小于1.0mg / dl或小于10 mg / l。

抗循环瓜氨酸肽(抗CCP)

CCP是可以指示Ra的存在的抗体。这是一个更新的,更准确的测试。当它是积极的时,有90%到95%likelihood that the person has RA. As well, it can be positive up to 15 years before a person develops RA.

范围结果是:

  • Negative: less than 20.0 U

  • Weak positive: 20.0-39.9 U

  • Positive: 40-59.9 U

  • 强阳性:超过或= 60.0 u

During the diagnosis process, you may also be tested for Lyme disease, which can include symptoms of fever, fatigue and joint pain, as well as for anemia, which can often occur with certain inflammatory chronic illnesses.

正如您对RA对待的那样,您也可能会测试肝脏和肾功能,以及胆固醇。这有助于您的医生密切关注您的内部器官,以便在任何系统问题上保持。

Vectra DA

Vectra DA是一种相对较新的测试,用于在能够被诊断出来的类风湿性关节炎的管理中。

它测量与RA活动相关的12个生物标志物,并且被认为比CRP或ESR更准确。您的分数将落在0-100的范围内:

  • 低疾病活动1-29

  • 适度疾病活动30-44

  • High disease activity 45-100

How to Understand Your Rheumatoid Arthritis

Now that you know what the tests measure and what the numbers mean, how do you use that information? Not as much as you might think.

除了抗CCP测试外,血液测试不是很准确。依靠它们作为诊断中的决定因素或评估您的健康状况可能会误导。事实上,大多数风湿病学家仅使用它们作为诊断和指南的确认工具治疗

例如,如果您获得血液测试的副本并注意到CRP或ESR高,您可能非常担心耀斑。事实是,这些测试测量了身体中的一般炎症,没有具体RA.inflammation。如果你燃烧,他们会上去,但如果你酝酿鼻窦感染,他们也会上升。

您的风湿病学者将重点关注身体检查和您对疼痛水平和生活质量的报告,以评估您的表现。如果你开始担心你的数字,请记住这一点。如果您的疼痛和能量水平是体面,并且您的关节没有显示出通常的疾病活动迹象(大多数情况下,这包括肿胀的关节),您可能是可以的。

有您的实验室工作副本是正确的。事实上,如果您必须改变医生或看到新专业人员,将记录录音可能是一个好主意。

注意血液测试是什么意思,但尽量不要obsess. Poring over your numbers or indulging your inner geek by considering graphing the results over time is probably not very healthy. Instead, talk to your doctor to get more information and support about blood tests.

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Lene Andersen, MSW

Lene Andersen is an author, health and disability advocate, and photographer living in Toronto. Lene (pronounced Lena) has lived with rheumatoid arthritis since she was four years old and uses her experience to help others with chronic illness. She has written several books, including Your Life with Rheumatoid Arthritis: Tools for Managing Treatment, Side Effects and Pain, and 7 Facets: A Meditation on Pain, as well as the award-winning blog, The Seated View. Lene serves on HealthCentral's Health Advocates Advisory Board, and is a Social Ambassador for the RAHealthCentral on Facebook page, facebook.com/rahealthcentral. She is also one of HealthCentral'sLive Bold,现在生活英雄 -看着她与ra的令人难以置信的生活之旅。