更多的证据表明,慢性压力会增加阿尔茨海默氏症的风险
A new doctoralthesis by Sara K. Bengtsson, Department of Clinical Sciences, Umeå University, Sweden, examines the reason why chronic stress can increase one's risk for Alzheimer's disease.
allopregnanolone,一种由a产生的类固醇之一body under stress,可以抑制一般大脑活动。孟斯森的论文表明,在遗传改变的小鼠模型中,慢性尼泊尔尼泊尔尼泊尔尼泊尔醌的血液升高水平加速了阿尔茨海默病的发育。
After a period of subjecting the mice to chronically elevated levels of the stress hormone allopregnanolone, tests showed high levels of beta-amyloids which corresponded to dysfunction among brain synapses in the mice. This did not occur after placebo treatment.
The effects were identified early in the disease development when the animals normally have intact memory function. Bengtsson's thesis suggests that a similar acceleration of chronic stress related Alzheimer's disease in humans could mean the difference between living independently at home and needing earlier professional care.
The idea of chronic stress as a risk factor for Alzheimer's disease isn't new. In 2011, scientists from the Max Planck Institute of Psychiatry in Munich discovered that the increased release ofstress hormones in ratsleads to generation of abnormally phosphorylated tau protein in the brain and ultimately, memory loss. Other studies also support this theory.
Limiting chronic stress
Dr. Kathleen Hall, author, stress expert and founder of the Stress Institute and the Mindful Living Network says that stress is the "greatest threat to our lives." Hall says that if we slow down and learn some relaxation techniques, it absolutely will affect our health outcome.
According to a Huffington Post interview with Dr. Hall, older adults should consider "physical exercises, brain training exercises, meditation, and the development of a strong social network to ward off stress and create a calmer lifestyle."
Study results can sometimes make us non-scientists a little cross-eyed. Yet we need to pay attention to new findings.
In modern life, taking time to relax and reduce stress can be hard to do, and even embarrassing to admit to. Successful people are busy, busy, busy, right? The only acceptable response to "what are you doing?" seems to be reciting an endless list of activities we must complete.
下次发现自己处于这种情况下,说:“我很抱歉,但我不能这样做,我在放松。”然后放松。追随霍尔博士的建议,您可能降低了开发阿尔茨海默病的风险,降低了慢性应力水平。
Resources:
Science Daily. (2013, March 14) How Chronic Stress Accelerates Alzheimer's Disease. Retrieved fromhttp://www.sciencedaily.com/releases/2013/03/130314085049.htm?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+sciencedaily%2Fmind_brain%2Falzheimers+%28ScienceDaily%3A+Mind+%26+Brain+News+--+Alzheimer%27s%29
Max Planck Institute of Psychiatry. (2011, May 26) Stress may increase risk for Alzheimer's disease. Retrieved fromhttp://www.mpg.de/4326511/stress_alzheimer?filter_order=L
Gregoire, C. (2012, March 18) New Findings Show How Chronic Stress Contributes To Development Of Alzheimer's Disease. Huffington Post. Retrieved fromhttp://www.huffingtonpost.com/2013/03/18/chronic-stress-alzheimers-cause_n_2885419.html
Huffington Post(2013年3月12日)压力和老化:压力影响50岁的5种方式(以及如何创造更轻的生活方式)。从...获得http://www.huffingtonpost.com/2013/03/12/stress-and-aging-10-ways-_n_2805468.html